Building the biopharma company of the future

Developing New Categories of Medicine

Our goal is to improve and extend the lives of patients through the development of new categories of medicine

Exploring the Brain Immune Gut (BIG) Axis

Focused on the crosstalk and biological processes associated with the brain-immune-gut interface

Giving Life to Science

Our goal is to improve and extend the lives of patients

Moving Medicine Forward

Discovery Reinvented

Publications -2017-09-19
Gamma Delta T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation

CD4(+) T regulatory cells (T(regs)), which express the Foxp3 transcription factor, play a critical role in the maintenance of immune homeostasis. Here, we show that in mice, T(regs) were most abundant in the colonic mucosa.

Full Article

Publications -2017-09-19
The Gut’s Clostridium Cocktail

Specific components of the microbiota—the microorganisms that normally colonize the body—can affect disease progression in mouse models of arthritis, central nervous system inflammation, diabetes, intestinal inflammation, and obesity.

Full Article
Publications -2017-06-01
Video game training enhances cognitive control in older adults

Cognitive controlis defined by a set of neural processes that allow us to interact with our complex environment in a goal-directed manner.


Media Coverage
PureTech's Lymphatic Leap

PureTech Health plc is launching a new branch of inquiry into the lymphatic system following discoveries that the network extends into the brain and could be used to deliver immunotherapies directly to tissues.


PureTech Health CEO Daphne Zohar to Present at The Wall Street Journal Health Forum on May 22, 2018 in Washington, D.C.
PureTech's Chief Scientific Officer Joe Bolen to present in keynote, "The Brain-Immune-Gut Super System and the Emergence of Human Chronic Disease" at MIT Lincoln Laboratory Advanced Research and Technology Symposium (ARTS) on March 6, 2018