Developing groundbreaking medicines

PureTech Health is developing therapeutics based on the biology and crosstalk of the Brain-Immune-Gut (BIG) axis. This emerging field of human biology underscores and unifies our two pipelines. View our corporate deck.

Our Affiliates pipeline

Our Affiliates pipeline includes seven clinical-stage platforms, including one product that has been cleared by the FDA and a second product candidate that has been filed with the FDA for review, and several other novel preclinical programs that have been developed in collaboration with some of the world's leading scientific experts.

Our Internal R&D pipeline

Our Internal R&D Pipeline is centered on tissue-selective immunomodulation for the treatment of oncology, autoimmune, and CNS-related disorders, with a near-term focus on targeting newly-discovered, foundational immunosuppressive mechanisms in oncology and novel approaches that harness the lymphatic infrastructure.


Our affiliates pipeline

Our Affiliates pipeline includes two pivotal stage programs and a number of clinical and pre-clinical programs that have been developed in collaboration with some of the world’s leading scientific experts.

Our internal pipeline

Our Internal pipeline leverages new insights into lymphatic biology and immune cell trafficking to advance novel therapeutic candidates.

Collaborating with Industry Pioneers Across Our Affiliates and Internal R&D Pipelines

Amgen Novartis Lilly Merck Boehringer Ingelheim Bristol-Myers Squibb Janssen Roche


  • Aging related immune disorders
  • Gut/Immune Ecosystem
  • Severe and Chronic Mental Health