Collaborative Drug Discovery

PureTech is developing highly differentiated medicines for dysfunctions of the Brain-Immune-Gut (BIG) axis. These latest scientific discoveries are being advanced across an extensive pipeline comprised of one FDA cleared product and 24 product candidates, of which 14 are clinical stage.

View our corporate deck.

Our Affiliates pipeline

The Affiliates pipeline includes seven clinical-stage platforms, including one product that has been cleared by the FDA and a second product candidate that has been filed with the FDA for review, and several other novel preclinical programs that have been developed in collaboration with some of the world's leading scientific experts.

Our Internal R&D pipeline

The internal programs are focused on harnessing the lymphatic system to treat devastating diseases including lymphatic disorders, intractable cancers, immunological diseases and CNS disorders. The lymphatic system is the central channel for immune cell trafficking, connects all tissues to regional lymph nodes and is essential for fluid balance.



Our affiliates pipeline

Our Affiliates pipeline includes two pivotal stage programs and a number of clinical and pre-clinical programs that have been developed in collaboration with some of the world’s leading scientific experts.

Our internal pipeline

Our Internal pipeline leverages new insights into lymphatic biology and immune cell trafficking to advance novel therapeutic candidates.

Collaborating with Industry Pioneers Across Our Affiliates and Internal R&D Pipelines

Amgen Novartis Lilly Merck Boehringer Ingelheim Bristol-Myers Squibb Janssen Roche


  • Aging related immune disorders
  • Gut/Immune Ecosystem
  • Severe and Chronic Mental Health