PureTech News
Publications
Publications 2017-09-19
Gamma Delta T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation

CD4(+) T regulatory cells (T(regs)), which express the Foxp3 transcription factor, play a critical role in the maintenance of immune homeostasis. Here, we show that in mice, T(regs) were most abundant in the colonic mucosa.

Full Article

Publications 2017-09-19
The Gut’s Clostridium Cocktail

Specific components of the microbiota—the microorganisms that normally colonize the body—can affect disease progression in mouse models of arthritis, central nervous system inflammation, diabetes, intestinal inflammation, and obesity.

Full Article
Publications 2017-06-19
Tunable Hydrogel for Local GI Modulation
Satiety and Glycemic Control-Enhancing properties of Gelesis100 presented at American Diabetes Association

The importance of fruits, vegetables, and wholegrains as part of a healthy diet is well documented, in part because of their abundance of naturally occurring dietary fibers.

Full article

Publications 2017-06-01
Cognitive Interference Processing
Video game training enhances cognitive control in older adults

Cognitive controlis defined by a set of neural processes that allow us to interact with our complex environment in a goal-directed manner.

FULL ARTICLE

Publications 2017-05-17
Tunable Hydrogel for Local GI Modulation
Satiety, Weight Loss, and Glycemic Control-Enhancing properties of Gelesis200 presented at European Congress on Obesity
Publications 2017-05-16
Tunable Hydrogel for Local GI Modulation
Pretreatment Fasting Glucose Determines Weight Loss on Mediterranean Diets presented at American Diabetes Association
Publications 2017-05-16
Tunable Hydrogel for Local GI Modulation
Pretreatment Fasting Glucose and Insulin Determine Weight Loss on New Nordic Diet presented at American Diabetes Association
Publications 2017-05-16
Tunable Hydrogel for Local GI Modulation
Pretreatment Fasting Glucose Predicts Weight Loss on High Fiber, Low Glycemic Load Diet presented at American Diabetes Association
Publications 2017-05-16
Cognitive Interference Processing
Improving late life depression and cognitive control through the use of therapeutic video game technology: A proof-of-concept randomized trial.
Publications 2017-05-01
Tunable Hydrogel for Local GI Modulation
Pretreatment Fasting Glucose and Insulin Determine Weight Loss Success on Low CHO vs. Low Fat Diet presented at American Diabetes Association

The struggle to curb the current obesity epidemic with an optimal diet has largely failed, giving rise to numerous insufficient approaches.

Full article

@PureTechH

Exploring the Brain Immune Gut Interface

Targeting serious diseases caused by dysfunctions in the brain-immune-gut axis

See Our Science