PureTech Health News
Publications
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Publications -2017-09-19
Gamma Delta T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation

CD4(+) T regulatory cells (T(regs)), which express the Foxp3 transcription factor, play a critical role in the maintenance of immune homeostasis. Here, we show that in mice, T(regs) were most abundant in the colonic mucosa.

Full Article

Publications -2017-09-19
The Gut’s Clostridium Cocktail

Specific components of the microbiota—the microorganisms that normally colonize the body—can affect disease progression in mouse models of arthritis, central nervous system inflammation, diabetes, intestinal inflammation, and obesity.

Full Article
Publications -2017-06-01
Video game training enhances cognitive control in older adults

Cognitive controlis defined by a set of neural processes that allow us to interact with our complex environment in a goal-directed manner.

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Press Releases
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Press Release - 2017-09-25
Tunable Hydrogel for Local GI Modulation
PureTech Health’s Gelesis Reports Significant Weight Loss with Excellent Safety Profile in Pivotal Study with Gelesis100

PureTech Health plc ("PureTech", LSE: PRTC), an advanced, clinical-stage biopharmaceutical company, is pleased to note that Gelesis, an affiliate of PureTech Health, today announced topline results from the pivotal weight loss study (GLOW) of one of its product candidates, Gelesis100.

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Media Coverage
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Media Coverage - 2017-10-11
Microbiome-Derived Immune Modulators
Six Grand Ideas to Fight the End of Antibiotics

Overuse of antibiotics has led them to becoming less and less effective to treat us when we’re sick – leaving scientists scrambling for a fix. Here are some of the best ideas to tackle one of the 21st Century's biggest challenges.

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Events
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Events - 2017-11-08
PureTech's Senior Associate, James Mutamba, presents on Commense Health and The Critical Role of the Early Microbiome in Childhood Health and Development at Microbiome World Congress Americas in Washington, DC.

With keynotes, interactive discussions, workshops and roundtables, this event is designed to tackle the most important challenges facing the flourising microbiome industry.

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Publications
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Publications - 2017-09-19
Gamma Delta T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation

CD4(+) T regulatory cells (T(regs)), which express the Foxp3 transcription factor, play a critical role in the maintenance of immune homeostasis. Here, we show that in mice, T(regs) were most abundant in the colonic mucosa.

Full Article

Brain-Immune-Gut Axis
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BIG Axis - 2017-10-19
A Spoonful of Sugar Could be the Medicine, Nature Magazine

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Exploring the Brain Immune Gut Interface

Targeting serious diseases caused by dysfunctions in the brain-immune-gut axis

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